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ARTANE trihexyphenidyl is not recommended for use in patients with tardive dyskinesia unless they have Trihexyphenidyl generic Best Price Parkinson’s disease. Psychiatric disturbances can result from Trihexyphenidyl generic Best Price use leading to overdosage to sustain continued euphoria. As with other anticholinergics, trihexyphenidyl may cause suppression of lactation.

Therefore, trihexyphenidyl should only be used if the expected benefit to the mother outweighs the potential risk to the infant. Pediatric Use Safety and effectiveness in pediatric patients have not been established.

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However, rare cases of death associated with trihexyphenidyl overdosages taken in conjunction with other leclerebruno.be agents have been reported or in patients with a compromised respiratory condition, Trihexyphenidyl Generic Best Price.

leclerebruno.be blood concentrations associated with the fatalities ranged from 0. Signs and Symptoms Overdosage with ARTANE trihexyphenidyl produces Trihexyphenidyl generic Best Price central symptoms of atropine intoxication the central anticholinergic syndrome. Correct diagnosis depends upon recognition of the peripheral signs of parasympathetic blockade, including dilated and sluggish pupils; warm, dry skin ; facial flushing; decreased secretions of the mouth, pharynx, nose, and bronchi ; foul-smelling breath; Trihexyphenidyl generic Best Price temperature; tachycardia, cardiac arrhythmias; decreased bowel sounds ; and urinary retention.

Neuropsychiatric signs such as delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, lip smacking and tasting movements, loss of memory, paranoia, combativeness, and seizures may be present. The condition can progress to stupor, coma, paralysis, cardiac and respiratory arrest, and death.

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Treatment Treatment of Trihexyphenidyl generic Best Price overdose involves symptomatic and supportive therapy. Gastric lavage or other methods to limit absorption should be instituted. Phenothiazines are contraindicated because the toxicity may be intensified due to their antimuscarinic action, causing coma.

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The dose may then Best Diflucan Prices increased by 2 mg increments at intervals of three to five Trihexyphenidyl generic Best Price, until a total of 6 to 10 mg is given daily. The total daily dose will depend upon what is found to be the optimal level. Many patients derive maximum benefit from this daily total of 6 to 10 mg, but some patients, chiefly those in the postencephalitic group, may require a Trihexyphenidyl generic Best Price daily dose of 12 to 15 mg.

The total daily dosage usually ranges between 5 and 15 mg, although, in some cases, these reactions have been satisfactorily controlled on as little as 1 mg daily.

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It may be advisable to commence therapy with a single 1 mg dose. If the extrapyramidal manifestations are not Trihexyphenidyl generic Best Price in a few hours, the subsequent doses may be progressively increased until satisfactory control is achieved. It is Trihexyphenidyl generic Best Price possible to maintain the patient on a reduced Trihexyphenidyl hydrochloride dosage after the reactions have remained under control for several days. Instances have been reported in which these reactions have remained in remission for long periods after Trihexyphenidyl hydrochloride therapy was discontinued. Concomitant Use of Trihexyphenidyl Hydrochloride with Levodopa When Trihexyphenidyl hydrochloride is used concomitantly with levodopa, the usual dose of each may need to be reduced.

Careful adjustment is necessary, depending on side effects and degree of symptom control.

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